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Love Your Gut Bugs

Microbiologists are shining a scientific spotlight on previously neglected inhabitants of our bodies. The 100 trillion bacteria that populate an average adult, living mainly in the guts, should be treated with more respect, recent research shows, because they play a vital role in maintaining human health.

Microbiologists are shining a scientific spotlight on previously neglected inhabitants of our bodies. The 100 trillion bacteria that populate an average adult, living mainly in the guts, should be treated with more respect, recent research shows, because they play a vital role in maintaining human health.

The latest study by Chinese scientists provides new evidence that the different types of microbes in the gut can help to explain why some people grow fat and others don’t. The microbiome, as it is known, turns out to be a risk factor for obesity, alongside eating too much, exercising too little and having the wrong genes. Our digestion has evolved to work with the help of a kilogramme or so of microbes; the way we extract calories from food and how fast our appetite is satisfied – two determinants of how much weight we put on – depend on the balance between the 200 to 300 bacterial species that live in a typical human gut.

As several recent studies have shown, this balance depends critically on what we eat and what drugs we take. People living on a modern western diet have a very different microbiome from their pre-industrial ancestors. And a study of elderly people in Ireland, published in the journal Nature this summer, showed a direct relationship between diet, bacterial diversity and wellbeing. Although more research is needed to prove the point, evidence is growing that a varied diet, including plenty of unprocessed fruit, vegetables and cereals, promotes the growth of beneficial bacteria in the human body – indicating another possible theme for public health campaigns.

At the same time scientists at Reading University and elsewhere are taking a more directed approach. They are designing and testing “prebiotic” dietary ingredients to select for a beneficial community of gut bugs that reduces the risk of obesity and associated problems such as diabetes.

Appreciation of the importance of nourishing a healthy human microbiome should also lend weight to a quite different public health campaign: the drive to cut over-prescribing of antibiotics for trivial or inappropriate infections. Although antibiotics are intended only to kill pathogens, there is collateral damage to other microbes, upsetting the bacterial balance. The other option is to increase the number of probiotic bacteria in the gut by supplementing with good quality, pure, high strength probiotics.

The message for the holiday period, as you eat your festive foods, is to remember that you are feeding not just yourself but all the bugs in your body. Treat them to a varied diet – and do not poison them with unnecessary medication.